[ | E-mail | Share ]
Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Fat cells (adipocytes) surround breast tumors and contribute to tumor growth by expressing factors that aid oncogenesis. Col6 is a protein that is highly expressed in adipocytes and its expression is further increased in both obesity and in breast cancer cells. In this issue of the Journal of Clinical Investigation, Phillip Scherer and Jiyoung Park of the University of Texas Southwestern Medical Center report that a portion of the Col6 protein, known as endotrophin, alters the tumor environment to promote tumor growth and metastasis in mice. Mice with reduced endotrophin expression had significantly less tumor burden and fewer metastases. These findings link obesity and cancer progression and suggest that endotrophin may serve as novel therapeutic target in the treatment of breast cancer.
###
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-10/joci-elo100312.php
m i a mia super bowl tom coughlin wes welker eli manning eli manning kelly clarkson national anthem
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.